Genotoxicity and cytotoxicity of zinc oxide and titanium dioxide in HEp-2 cells

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Genotoxicity and cytotoxicity of zinc oxide and titanium dioxide in HEp-2 cells.

AIMS The rapidly growing industrial and medical use of nanomaterials, especially zinc oxide and titanium dioxide, has led to growing concerns about their toxicity. Accordingly, the intrinsic genotoxic and cytotoxic potential of these nanoparticles have been evaluated. MATERIALS & METHODS Using a HEp-2 cell line, cytotoxicity was tested along with mitochondrial activity and neutral red uptake ...

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ژورنال

عنوان ژورنال: Nanomedicine

سال: 2010

ISSN: 1743-5889,1748-6963

DOI: 10.2217/nnm.10.52